Description

2-(2-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-purity fluorinated pyrimidine derivative, a critical building block in modern pharmaceutical and agrochemical research. Its core value lies in its unique molecular scaffold, which is essential for synthesizing compounds with targeted biological activity. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators leveraging the fluorophenyl-pyrimidine motif.
• Chemical Biology: Serves as a precursor for fluorescent probes or molecular tags due to its modifiable ester and aromatic groups.
• Material Science: Potential building block for organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2-(2-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	960198-52-1
Molecular Formula	C12H9FN2O2
Molecular Weight	232.21 g/mol
Synonyms	Methyl 2-(2-fluorophenyl)pyrimidine-5-carboxylate; 2-(2-Fluorophenyl)-5-pyrimidinecarboxylic acid methyl ester; 5-(Methoxycarbonyl)-2-(2-fluorophenyl)pyrimidine; 2-(2-Fluorophenyl)pyrimidine-5-carboxylic acid methyl ester; 960198-52-1; 2-(2-Fluorophenyl)-5-(methoxycarbonyl)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluorophenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced organic synthesis. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.