Description

2-(3,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. Its value lies in its precise molecular architecture, which is critical for constructing complex molecules with specific electronic and steric properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl-pyrimidine scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile aldehyde component in cross-coupling reactions, condensations, and reductive amination for library synthesis.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(3,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde
CAS No.	960198-48-5
Molecular Formula	C11H6F2N2O
Molecular Weight	220.18 g/mol
Synonyms	5-Formyl-2-(3,5-difluorophenyl)pyrimidine; 2-(3,5-Difluorophenyl)-5-pyrimidinecarboxaldehyde; 2-(3,5-Difluorophenyl)pyrimidine-5-carboxaldehyde; 960198-48-5; 5-Pyrimidinecarboxaldehyde, 2-(3,5-difluorophenyl)-; 2-(3,5-Difluorophenyl)-5-formylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Difluorophenyl)Pyrimidine-5-Carbaldehyde is produced under strict quality management protocols. We ensure compliance with cGMP standards where applicable, and our in-house analytical laboratory performs rigorous testing using advanced techniques like HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.