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2-Fluoro-3-(Hydroxymethyl)Phenol CAS NO 960001-66-5


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CAS No.:960001-66-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-3-(Hydroxymethyl)Phenol is a versatile fluorinated phenolic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a hydroxymethyl group on the phenol ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
  • Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and optical devices.
  • Polymer Modification: Incorporated as a functional monomer to introduce fluorine and phenolic groups into specialty polymers, improving chemical resistance and surface properties.
  • Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination chemistry and creating specialized chemical libraries.
  • Fine Chemical Production: Acts as a building block for synthesizing complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name 2-Fluoro-3-(Hydroxymethyl)Phenol
CAS No. 960001-66-5
Molecular Formula C7H7FO2
Molecular Weight 142.13 g/mol
Synonyms 3-(Hydroxymethyl)-2-fluorophenol; 2-Fluoro-3-hydroxybenzyl alcohol; 2-Fluoro-3-(hydroxymethyl)phenol; 2-Fluoro-3-hydroxybenzyl alcohol; 2-Fluoro-3-methylolphenol; 3-Fluoro-2-hydroxybenzyl alcohol (common misnomer); 2-Fluororesorcinol monomethylol; F-HMP
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Quality Control

Our production of 2-Fluoro-3-(Hydroxymethyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in cGMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent oxidation or degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Unknown Impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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