Description

3-Fluoro-4-Methylthiophenol is a specialized organosulfur compound featuring a thiol group and a fluorine substituent on a methylated benzene ring. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for introducing fluorinated aromatic thiol motifs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, especially in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and coordination chemistry.
• Material Science: Intermediate in the production of fluorinated polymers, liquid crystals, and advanced electronic materials.
• Chemical Research: A versatile reagent for introducing the 3-fluoro-4-methylphenylthio group into complex molecular architectures.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific sulfur-containing aromatic compounds, though high purity grades are required.

Basic Information

Product Name	3-Fluoro-4-Methylthiophenol
CAS No.	13333-79-4
Molecular Formula	C7H7FS
Molecular Weight	142.19 g/mol
Synonyms	3-Fluoro-4-methylbenzenethiol; 4-Methyl-3-fluorobenzenethiol; (3-Fluoro-4-methylphenyl)thiol; 3-Fluoro-p-toluenethiol; 3-Fluoro-4-methylthiophenol; 3-Fluoro-4-methylphenyl mercaptan; 13333-79-4; 3-Fluoro-4-methyl-benzenethiol
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylthiophenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept tightly sealed when not in use and away from heat, sparks, and open flames. Store separately from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.