Description

4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol is a high-purity, functionalized biphenyl derivative characterized by a phenolic hydroxyl group and a trifluoromethyl substituent. This compound is a valuable advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a core structure for creating novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Used as a building block for high-performance electronic materials, where the biphenyl core and fluorine atoms contribute to desired electronic and mesomorphic properties.
• Polymer Science: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and optical characteristics.
• Organic Synthesis & Catalysis: Acts as a ligand precursor or a functionalized scaffold in cross-coupling reactions and other catalytic processes.
• Academic & Industrial R&D: Employed in research laboratories for method development and the exploration of new chemical entities.

Basic Information

Product Name	4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol
CAS No.	10355-13-2
Molecular Formula	C₁₃H₉F₃O
Molecular Weight	238.21 g/mol
Synonyms	4'-(Trifluoromethyl)biphenyl-4-ol; 4-Hydroxy-4'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-ol, 4'-(trifluoromethyl)-; 4-(4-Hydroxyphenyl)benzotrifluoride; p-Hydroxy-p'-(trifluoromethyl)biphenyl; 4-(Trifluoromethyl)[1,1'-biphenyl]-4'-ol; 10355-13-2
EINECS	Contact for details

Quality Control

Our 4'-(Trifluoromethyl)[1,1'-Biphenyl]-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-compliant pharmaceutical synthesis and advanced R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.