Description

4-Chloro-Tetrafluorothiophenol is a specialized fluorinated organosulfur compound with a unique combination of a thiol group and a perchlorinated aromatic ring. This structure makes it a valuable intermediate for introducing sulfur and fluorine functionalities into target molecules, enabling the fine-tuning of material properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring high-performance chemical building blocks.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated thioether or disulfide linkages to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for creating novel herbicides, fungicides, and insecticides where the fluorine atoms improve lipophilicity and membrane penetration.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorine-containing heterocyclic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce reactive thiol groups into polymer chains or as a chain-transfer agent in radical polymerization to control molecular weight.
• Ligand Synthesis for Catalysis: Useful for preparing fluorinated thiol-based ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Surface Functionalization: Can be used to modify material surfaces (e.g., gold nanoparticles) via the strong affinity of the thiol group, imparting specific chemical properties.

Basic Information

Product Name	4-Chloro-Tetrafluorothiophenol
CAS No.	13634-93-0
Molecular Formula	C6HClF4S
Molecular Weight	216.58 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-chlorobenzenethiol; 4-Chloro-2,3,5,6-tetrafluorobenzenethiol; 4-Chloro-2,3,5,6-tetrafluorothiophenol; p-Chlorotetrafluorothiophenol; Perchlorofluorothiophenol; C6HClF4S; 13634-93-0
EINECS	Contact for details

Quality Control

Our 4-Chloro-Tetrafluorothiophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizers and bases. Due to its nature as a strong acid/organic solvent and highly volatile compound, it is recommended to store at controlled room temperature (15-25°C) under an inert atmosphere if possible to minimize degradation and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.