Description

4-Nitro-2-Trifluoromethylphenol is a versatile fluorinated phenolic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and trifluoromethyl substituents, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, pesticides, and plant growth regulators, leveraging the bioactivity of the nitro-phenol and fluorine-containing groups.
• Pharmaceutical Synthesis: Serves as a crucial building block for developing active pharmaceutical ingredients (APIs), particularly in creating molecules with enhanced metabolic stability and bioavailability.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes and pigments, where the nitro group contributes to color development and the trifluoromethyl group can alter solubility and lightfastness.
• Liquid Crystal and Electronic Materials: Acts as an intermediate for synthesizing fluorinated compounds used in liquid crystal displays (LCDs) and other electronic materials.
• Polymer Modification: Employed to introduce fluorinated phenolic units into polymer chains, enhancing properties like chemical resistance, thermal stability, and surface characteristics.
• Research & Development: Widely used in academic and industrial R&D labs for exploring new chemical reactions, catalytic processes, and material science applications.

Basic Information

Product Name	4-Nitro-2-Trifluoromethylphenol
CAS No.	1548-61-4
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	2-Hydroxy-5-nitrobenzotrifluoride; 2-Trifluoromethyl-4-nitrophenol; 4-Nitro-α,α,α-trifluoro-o-cresol; 5-Nitro-2-(trifluoromethyl)phenol; Phenol, 4-nitro-2-(trifluoromethyl)-; NSC 404080; 4-Nitro-2-trifluoromethylphenol
EINECS	Contact for details

Quality Control

Our 4-Nitro-2-Trifluoromethylphenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthesis and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. Due to its phenolic and nitro-substituted nature, it should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.