Description

4-Amino-2-(Trifluoromethyl)Phenol is a versatile aromatic compound featuring both an amino and a phenolic hydroxyl group, substituted with a trifluoromethyl moiety. This unique structure makes it a valuable high-purity intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D, agrochemical, and specialty chemical manufacturers for constructing complex molecules where fluorine substitution is critical for enhancing biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized, high-performance colorants.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine into polymer chains, altering surface properties and chemical resistance.
• Research & Development: Essential for academic and industrial research in medicinal chemistry and material science.

Basic Information

Product Name	4-Amino-2-(Trifluoromethyl)Phenol
CAS No.	1535-76-8
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-Amino-5-hydroxybenzotrifluoride; 2-Trifluoromethyl-4-aminophenol; 4-Amino-α,α,α-trifluoro-o-cresol; 5-Amino-2-hydroxybenzotrifluoride; 2-Hydroxy-5-aminobenzotrifluoride; 4-Amino-2-(trifluoromethyl)benzenol; 2-Trifluoromethyl-4-hydroxyaniline
EINECS	Contact for details

Quality Control

Our 4-Amino-2-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our production can meet the stringent requirements for GMP-grade intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.