Description

4-(Aminomethyl)-3-Fluorophenol is a versatile fluorinated aromatic building block containing both a phenolic hydroxyl group and a primary aminomethyl functionality. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and specialty organic materials. It is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated phenolic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic displays and organic light-emitting diodes due to its aromatic and polar characteristics.
• Polymer Modification: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal or chemical resistance.
• Peptide Mimetics & Bioconjugation: The reactive amine and phenol groups allow for its use in constructing peptide analogs or as a linker in bioconjugation chemistry.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and organic synthesis.

Basic Information

Product Name	4-(Aminomethyl)-3-Fluorophenol
CAS No.	754971-62-5
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	3-Fluoro-4-(aminomethyl)phenol; 4-(Aminomethyl)-3-fluorophenol; 2-Fluoro-4-hydroxybenzylamine; (3-Fluoro-4-hydroxyphenyl)methanamine; 4-Hydroxy-3-fluorobenzylamine; Benzenemethanamine, 3-fluoro-4-hydroxy-; 754971-62-5
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent oxidation and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.