Description

1-(2-Chloro-7-(Pentan-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant commercial value for its role as a critical building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and immunology research.
• Kinase Inhibitor Development: Serves as a core scaffold for constructing potent and selective kinase inhibitors due to its privileged pyrrolopyrimidine structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to improve drug candidate efficacy and pharmacokinetic properties.
• Biochemical Probe Synthesis: Employed in creating labeled or modified compounds for use in mechanistic studies and target validation within biological systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	1-(2-Chloro-7-(Pentan-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Ethanone
CAS No.	959799-20-3
Molecular Formula	C₁₃H₁₆ClN₃O
Molecular Weight	265.74 g/mol
Synonyms	1-(2-Chloro-7-(1-ethylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)ethanone; 2-Chloro-7-(pentan-3-yl)-6-acetyl-7H-pyrrolo[2,3-d]pyrimidine; 6-Acetyl-2-chloro-7-(1-ethylpropyl)-7H-pyrrolo[2,3-d]pyrimidine; 959799-20-3; Ethanone, 1-[2-chloro-7-(1-ethylpropyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-; 1-(2-Chloro-7-pentan-3-yl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-7-(Pentan-3-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-6-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be handled under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.