Description

n-Arachidonoyl-3-Hydroxy-γ-Aminobutyric Acid is a specialized synthetic cannabinoid receptor ligand, structurally derived from arachidonic acid and γ-aminobutyric acid (GABA). This compound is of significant interest for advanced pharmacological research, particularly in the study of the endocannabinoid system and its modulation. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and developers in the pharmaceutical and biotechnology sectors. Its precise structure allows for targeted investigation into receptor binding and signal transduction pathways.

Application

• Pharmacological Research: A key reference standard for studying cannabinoid receptor (CB1/CB2) interactions, affinity, and functional activity.
• Neuroscience Studies: Used in vitro and in vivo to investigate the role of the endocannabinoid system in neurological processes and disorders.
• Drug Discovery & Development: Serves as a high-purity intermediate or building block for the synthesis of novel therapeutic agents targeting pain, inflammation, and neurological conditions.
• Biochemical Assay Development: Employed in the development and validation of screening assays for receptor binding and enzyme inhibition studies.
• Academic Research: Utilized in university and institutional labs for fundamental research into lipid signaling and neuromodulation.
• Analytical Standard: Provides a certified reference material for method development and quality control in analytical laboratories (e.g., HPLC, LC-MS).

Basic Information

Product Name	n-Arachidonoyl-3-Hydroxy-γ-Aminobutyric Acid
CAS No.	959761-62-7
Molecular Formula	C₂₄H₃₉NO₄
Molecular Weight	405.57 g/mol
Synonyms	N-Arachidonoyl-3-hydroxy-GABA; 3-Hydroxy-N-arachidonoyl-GABA; 3-Hydroxy-N-arachidonoyl-γ-aminobutyric acid; Arachidonoyl 3-hydroxy-GABA; (5Z,8Z,11Z,14Z)-N-(3-Hydroxy-4-aminobutyl)icosa-5,8,11,14-tetraenamide; GABA arachidonoyl derivative; Endocannabinoid-GABA conjugate
EINECS	Contact for details

Quality Control

Our n-Arachidonoyl-3-Hydroxy-γ-Aminobutyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.