Description

n-(9H-Fluoren-9-Yl)Methoxy]Carbonyl (2S,3S)-3-Amino-2-Hydroxy-3-o-Tolylpropionic Acid is a sophisticated, optically pure amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is critical for the controlled synthesis of complex peptides and peptidomimetics, enabling precise molecular assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and advanced biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the sequential assembly of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of potential drug candidates, particularly those targeting specific protein-protein interactions.
• Peptidomimetic Design: Essential for creating non-natural peptide analogs with enhanced stability, bioavailability, or biological activity.
• Bioconjugation: Acts as a precursor for linking peptides to other molecules, such as dyes, polymers, or solid surfaces, for diagnostic and research applications.
• Chemical Biology Research: Employed in studies exploring enzyme mechanisms, receptor-ligand binding, and cellular signaling pathways.
• Library Synthesis: Used in combinatorial chemistry to generate diverse arrays of compounds for high-throughput screening.

Basic Information

Product Name	n-(9H-Fluoren-9-Yl)Methoxy]Carbonyl (2S,3S)-3-Amino-2-Hydroxy-3-o-Tolylpropionic Acid
CAS No.	959578-55-3
Molecular Formula	C25H23NO5
Molecular Weight	417.46 g/mol
Synonyms	Fmoc-(2S,3S)-3-Amino-2-hydroxy-3-(2-methylphenyl)propanoic Acid; (2S,3S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-3-(2-methylphenyl)propanoic Acid; Fmoc-Thr(2-MePh)-OH; Fmoc-3-Amino-2-hydroxy-3-o-tolylpropionic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-2-hydroxy-3-(2-methylphenyl)propanoic Acid; (2S,3S)-3-(Fmoc-amino)-2-hydroxy-3-(o-tolyl)propionic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee high chemical and chiral purity, which is essential for reproducible research and development outcomes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.