Description

Pyrido[2,3-D]Pyrimidine-2,4,7(1H,3H,8H)-Trione, 5-Azido-1,3,8-Trimethyl-6-Nitro- is a specialized heterocyclic organic compound featuring a unique pyridopyrimidine trione core functionalized with azido and nitro groups. This complex molecular architecture makes it a valuable high-purity building block for advanced research and development in medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzymatic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: The azido group allows for bioorthogonal click chemistry, enabling the creation of probes for studying biological processes.
• Agrochemical Research: Potential application as an intermediate in the development of new herbicides or plant growth regulators.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular entity.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidine-2,4,7(1H,3H,8H)-Trione, 5-Azido-1,3,8-Trimethyl-6-Nitro-
CAS No.	959576-27-3
Molecular Formula	C10H9N7O5
Molecular Weight	307.22 g/mol
Synonyms	5-Azido-1,3,8-trimethyl-6-nitropyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione; 1,3,8-Trimethyl-5-azido-6-nitro-1H,3H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione; 5-Azido-1,3,8-trimethyl-6-nitro-1H,3H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione; 959576-27-3; Azidomethylnitropyridopyrimidinetrione; 5-Azido-6-nitro-1,3,8-trimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications, with documentation tailored to meet rigorous audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.