Description

n-(9H-Fluoren-9-Yl)Methoxy]Carbonyl (2S,3S)-3-Amino-2-Hydroxy-3-(2-Methoxy-Phenyl)Propionic Acid is a sophisticated, optically pure amino acid derivative protected with the Fmoc group, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in enabling the precise construction of complex peptide and peptidomimetic structures with defined stereochemistry. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative in Fmoc-based peptide assembly for research and production.
• Peptidomimetic Design: Integral for developing non-peptide compounds that mimic the structure and function of natural peptides in drug discovery.
• Chemical Biology & Proteomics: Employed in the synthesis of labeled peptides and molecular probes for studying biological mechanisms.
• Asymmetric Synthesis: Serves as a starting material or intermediate for constructing complex chiral molecules in medicinal chemistry.
• Academic & Industrial R&D: Used in research laboratories for exploring new synthetic methodologies and novel bioactive compounds.

Basic Information

Item	Details
Product Name	n-(9H-Fluoren-9-Yl)Methoxy]Carbonyl (2S,3S)-3-Amino-2-Hydroxy-3-(2-Methoxy-Phenyl)Propionic Acid
CAS No.	959576-01-3
Molecular Formula	C25H23NO6
Molecular Weight	433.45 g/mol
Synonyms	Fmoc-(2S,3S)-3-Amino-2-hydroxy-3-(2-methoxyphenyl)propionic acid; (2S,3S)-2-Hydroxy-3-[(9H-fluoren-9-ylmethoxy)carbonylamino]-3-(2-methoxyphenyl)propanoic acid; Fmoc-AHP-OH(2-MeO); Fmoc-3-Amino-2-hydroxy-3-(2-methoxyphenyl)propionic acid; (2S,3S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-3-(2-methoxyphenyl)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-2-hydroxy-3-(2-methoxyphenyl)propionic acid; Fmoc-protected β-hydroxy tyrosine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity specifications suitable for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and related substances are available for every batch upon request. Our quality system is designed to support applications requiring traceability and consistent performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.