Description

Fmoc-L-3-Carbamoylphe CAS NO 959573-22-9 is a protected amino acid derivative, specifically an Fmoc-protected phenylalanine analog with a carbamoyl substituent on the aromatic ring. This compound is a critical high-purity building block for solid-phase peptide synthesis (SPPS), enabling the precise incorporation of modified amino acids into complex peptide sequences. It is essential for researchers and manufacturers in pharmaceutical R&D, particularly in developing therapeutic peptides and peptidomimetics where structural modification is required for activity or stability.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides.
• Pharmaceutical Research: Building block for the development of novel therapeutic peptides targeting various diseases.
• Peptidomimetic Design: Used to create modified peptide backbones with enhanced metabolic stability or receptor binding affinity.
• Bioconjugation: Intermediate for attaching peptide sequences to other molecules, surfaces, or carriers.
• Chemical Biology Probes: Synthesis of labeled or tagged peptides for studying protein-protein interactions and cellular processes.
• Academic & Institutional Research: Fundamental research in organic chemistry, medicinal chemistry, and biochemistry.

Basic Information

Product Name	Fmoc-L-3-Carbamoylphe
CAS No.	959573-22-9
Molecular Formula	C25H22N2O5
Molecular Weight	430.46 g/mol
Synonyms	Fmoc-3-Carbamoyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-carbamoyl-L-phenylalanine; Fmoc-L-3-(aminocarbonyl)phenylalanine; Fmoc-3-Carbamoylphe-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(3-carbamoylphenyl)propanoic acid; Fmoc-Phe(3-CONH2)-OH; Nα-Fmoc-3-carbamoyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Fmoc-L-3-Carbamoylphe is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity verification. A detailed Certificate of Analysis (COA) is provided, documenting identity, assay, and impurity profiles to support regulatory filings and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.