Description

2H-Pyrazolo[3,4-D]Pyrimidine, 4,6-Dichloro-2-Methyl- is a high-value heterocyclic building block and key pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies developing targeted therapies, including kinase inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for oncology and antiviral applications.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing potent and selective kinase inhibitors, a major class of therapeutic agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and scale-up of complex organic molecules.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2H-Pyrazolo[3,4-D]Pyrimidine, 4,6-Dichloro-2-Methyl-
CAS No.	959432-77-0
Molecular Formula	C7H5Cl2N4
Molecular Weight	219.05 g/mol
Synonyms	4,6-Dichloro-2-methyl-2H-pyrazolo[3,4-d]pyrimidine; 4,6-Dichloro-2-methylpyrazolo[3,4-d]pyrimidine; 2-Methyl-4,6-dichloro-2H-pyrazolo[3,4-d]pyrimidine; 4,6-Dichloro-2-methyl-1H-pyrazolo[3,4-d]pyrimidine; 959432-77-0; Pyrazolo[3,4-d]pyrimidine, 4,6-dichloro-2-methyl-
EINECS	Contact for details

Quality Control

Our 2H-Pyrazolo[3,4-D]Pyrimidine, 4,6-Dichloro-2-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.