Description

4-Bromo-2-Methoxypyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the strategic reactivity of the bromine atom, enabling efficient cross-coupling reactions for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the pyrimidine moiety.
• Chemical Biology & Proteomics: Employed as a tagging or linking agent in the design of molecular probes and bioconjugates.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new reaction pathways in heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-2-Methoxypyrimidine
CAS No.	959240-72-3
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	2-Methoxy-4-bromopyrimidine; 4-Bromo-2-methoxypyrimidine; 4-Bromo-2-pyrimidinyl methyl ether; Pyrimidine, 4-bromo-2-methoxy-; 959240-72-3
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.