Description

(1-Oxopyrrolo[1,2-D][1,2,4]Triazin-2(1H)-Yl)Acetonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is essential for medicinal chemistry research and development teams, custom synthesis providers, and manufacturers of high-value specialty chemicals targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel heterocyclic libraries in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Used by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Oncology Drug Development: Integral to the research and production pathways of investigational anti-cancer agents.
• Antiviral Agent Synthesis: Employed in the development of new therapeutic compounds designed to combat viral infections.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(1-Oxopyrrolo[1,2-D][1,2,4]Triazin-2(1H)-Yl)Acetonitrile
CAS No.	959240-68-7
Molecular Formula	C8H6N4O
Molecular Weight	174.16 g/mol
Synonyms	2-(1-Oxopyrrolo[1,2-d][1,2,4]triazin-2(1H)-yl)acetonitrile; Pyrrolo[1,2-d][1,2,4]triazin-2(1H)-ylacetonitrile, 1-oxo-; 959240-68-7; (1-Oxo-1H-pyrrolo[1,2-d][1,2,4]triazin-2-yl)acetonitrile; Acetonitrile, (1-oxo-1H-pyrrolo[1,2-d][1,2,4]triazin-2-yl)-
EINECS	Contact for details

Quality Control

Our (1-Oxopyrrolo[1,2-D][1,2,4]Triazin-2(1H)-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.