Description

2,4-Dichloro-5-Iodoquinazoline is a high-purity halogenated quinazoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, where the chlorine and iodine atoms serve as distinct handles for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel kinase inhibitors and other biologically active heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the quinazoline core's bioactivity.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitutions to create diverse quinazoline libraries.
• Material Science Research: Serves as a starting material for synthesizing organic electronic materials and fluorescent dyes.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2,4-Dichloro-5-Iodoquinazoline
CAS No.	959237-30-0
Molecular Formula	C8H3Cl2IN2
Molecular Weight	324.93 g/mol
Synonyms	5-Iodo-2,4-dichloroquinazoline; 2,4-Dichloro-5-iodo-quinazoline; Quinazoline, 2,4-dichloro-5-iodo-; 959237-30-0; AKOS015903991; 2,4-dichloro-5-iodoquinazoline; 2,4-Dichloro-5-iodo-quinazoline; AS-87233
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-5-Iodoquinazoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.