Description

2-Methylthio-4-Bromopyrimidine is a high-purity brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable selective cross-coupling and substitution reactions, facilitating the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom is highly reactive in Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Nucleophilic Substitution: The methylthio group can be displaced to introduce diverse amine or alkoxy functionalities.
• Chemical Biology: Useful for synthesizing probes and labeled compounds for biochemical studies.

Basic Information

Product Name	2-Methylthio-4-Bromopyrimidine
CAS No.	959236-97-6
Molecular Formula	C5H5BrN2S
Molecular Weight	205.08 g/mol
Synonyms	4-Bromo-2-(methylthio)pyrimidine; 2-(Methylthio)-4-bromopyrimidine; 4-Bromo-2-methylsulfanylpyrimidine; 2-Methylmercapto-4-bromopyrimidine; 959236-97-6; 4-Bromo-2-methylthiopyrimidine; Pyrimidine, 4-bromo-2-(methylthio)-; 4-Bromo-2-(methylsulfanyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Methylthio-4-Bromopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.