Description

8-Iodoquinazoline-2,4(1H,3H)-Dione is a high-value, halogenated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique iodine-substituted structure makes it a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Potential monomer or precursor for creating specialty polymers, ligands for metal-organic frameworks (MOFs), or organic electronic materials.
• Chemical Biology: Employed in the development of molecular probes, enzyme inhibitors, and tools for studying biological pathways.
• Academic & Contract Research: Essential for synthetic methodology development, heterocyclic chemistry research, and discovery chemistry projects in academic and CRO settings.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of complex, customer-specific molecules for various industrial applications.

Basic Information

Product Name	8-Iodoquinazoline-2,4(1H,3H)-Dione
CAS No.	959236-79-4
Molecular Formula	C8H5IN2O2
Molecular Weight	288.04 g/mol
Synonyms	8-Iodo-1H-quinazoline-2,4-dione; 8-Iodoquinazoline-2,4-diol; 8-Iodobarbituric Acid (quinazoline analog); 8-Iodo-2,4-dihydroxyquinazoline; 8-Iodo-2,4(1H,3H)-quinazolinedione; IQD; 8-Iodoquinazolinedione
EINECS	Contact for details

Quality Control

Our 8-Iodoquinazoline-2,4(1H,3H)-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.