Description

1,3-Piperidinedicarboxylic Acid, 3-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine scaffold with an allyl and a tert-butyl ester functional group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors due to its piperidine core.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Employed in the synthesis of tool compounds and molecular probes for biological pathway investigation.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Item	Detail
Product Name	1,3-Piperidinedicarboxylic Acid, 3-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) Ester
CAS No.	959236-11-4
Molecular Formula	C15H23NO4
Molecular Weight	281.35 g/mol
Synonyms	tert-Butyl 3-allylpiperidine-1,3-dicarboxylate; 3-Allyl-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid; 1-Boc-3-allylpiperidine-3-carboxylic acid; 3-Allyl-1-N-Boc-piperidine-3-carboxylic acid; 1-(tert-Butoxycarbonyl)-3-(2-propen-1-yl)piperidine-3-carboxylic acid; 3-Allyl-1-((tert-butoxy)carbonyl)piperidine-3-carboxylic acid; 959236-11-4
EINECS	Contact for details

Quality Control

Every batch of our 1,3-Piperidinedicarboxylic Acid, 3-(2-Propen-1-Yl)-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for sensitive pharmaceutical R&D applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.