Description

2,4-Difluoro-3-Methylphenol is a fluorinated phenolic compound of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile and critical building block for constructing complex molecular architectures. This intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated aromatic motifs that can dramatically alter the biological activity and physicochemical properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluoro-methylphenol moiety enhances lipophilicity and metabolic stability.
• Liquid Crystal & Electronic Materials: Used in the research and production of fluorinated liquid crystals and organic semiconductors, where its structure contributes to desired dielectric and self-assembly properties.
• Polymer Modification: Acts as a monomer or additive for creating specialty polymers with improved chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, multi-functional aromatic compounds for various R&D applications.

Basic Information

Product Name	2,4-Difluoro-3-Methylphenol
CAS No.	959091-59-9
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	3-Methyl-2,4-difluorophenol; 2,4-Difluoro-3-methylphenol; 2,4-Difluoro-m-cresol; 3-Methyl-2,4-difluorobenzenol; Phenol, 2,4-difluoro-3-methyl-; 959091-59-9; 2,4-Difluoro-3-methyl-phenol
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Methylphenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.