Description

2H-Pyrazolo[4,3-D]Pyrimidin-7-Amine, 3-Bromo- is a high-purity, brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Used as a tool compound or reference standard in enzymatic assays and biological screening.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value heterocyclic molecules for various applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for clinical trial materials.

Basic Information

Product Name	2H-Pyrazolo[4,3-D]Pyrimidin-7-Amine, 3-Bromo-
CAS No.	959081-27-7
Molecular Formula	C5H5BrN6
Molecular Weight	229.04 g/mol
Synonyms	3-Bromo-2H-pyrazolo[4,3-d]pyrimidin-7-amine; 3-Bromo-7-amino-2H-pyrazolo[4,3-d]pyrimidine; 3-Bromo-7-aminopyrazolopyrimidine; 959081-27-7; 3-Bromo-7-azaindazole-7-amine (informal); Brominated pyrazolopyrimidine amine; 3-Br-7-NH2-PP
EINECS	Contact for details

Quality Control

Our 2H-Pyrazolo[4,3-D]Pyrimidin-7-Amine, 3-Bromo- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.