Description

3-Furancarboxylic Acid, Trimethylsilyl Ester is a specialized organosilicon derivative of furan-3-carboxylic acid, serving as a valuable protected intermediate in advanced organic synthesis. Its primary commercial value lies in its role as a versatile building block for the development of pharmaceuticals, agrochemicals, and functional materials, where it facilitates specific coupling reactions and protects the carboxylic acid functionality. This compound is particularly relevant for R&D chemists and process development scientists in fine chemical, pharmaceutical, and material science industries seeking high-purity synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those containing furan or heterocyclic motifs.
• Agrochemical Synthesis: Used as a building block for creating novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a precursor in the development of organic semiconductors, conductive polymers, and specialty coatings.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions where a protected carboxyl group is required.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands for metal complexes and organocatalysts used in asymmetric synthesis.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex aroma chemicals and flavoring agents.

Basic Information

Product Name	3-Furancarboxylic Acid, Trimethylsilyl Ester
CAS No.	959012-34-1
Molecular Formula	C9H14O3Si
Molecular Weight	198.29 g/mol
Synonyms	Trimethylsilyl 3-furoate; 3-Furoic Acid Trimethylsilyl Ester; 3-Carboxyfuran Trimethylsilyl Ester; Furan-3-carboxylic Acid Trimethylsilyl Ester; TMS 3-Furoate; (Furan-3-yl)(trimethylsilyloxy)methanone; Trimethylsilyl Furancarboxylate
EINECS	Contact for details

Quality Control

Every batch of 3-Furancarboxylic Acid, Trimethylsilyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.