Description

2H-Purin-2-One, 1,3-Dihydro-6-Nitroso- is a specialized purine derivative and a key nitroso-functionalized intermediate in advanced organic synthesis. This compound matters for its role in constructing complex heterocyclic scaffolds, which are fundamental to developing novel active pharmaceutical ingredients (APIs) and biochemical probes. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, nucleotide chemistry, and the development of targeted therapies.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel purine-based drug candidates, including kinase inhibitors and antiviral agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive molecules and optimize lead compounds.
• Nucleotide Analog Synthesis: Serves as a precursor in the development of modified nucleosides and nucleotides for biochemical research and potential therapeutics.
• Biochemical Probe Development: Employed to create labeled or tagged molecules for studying enzyme mechanisms and cellular pathways.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing complex heterocyclic systems via nitroso group chemistry.

Basic Information

Product Name	2H-Purin-2-One, 1,3-Dihydro-6-Nitroso-
CAS No.	958825-58-6
Molecular Formula	C5H3N5O2
Molecular Weight	165.11 g/mol
Synonyms	6-Nitroso-1H-purine-2(3H)-one; 6-Nitrosopurine-2-one; 6-Nitroso-2,3-dihydro-1H-purin-2-one; 6-Nitrosohypoxanthine; 1H-Purin-2(3H)-one, 6-nitroso-; 6-Nitroso-1H-purin-2(3H)-one; 6-Nitroso-2,3-dihydropurin-2-one; 6-Nitrosopurine-2(1H,3H)-one
EINECS	Contact for details

Quality Control

Our 2H-Purin-2-One, 1,3-Dihydro-6-Nitroso- is produced under strict quality management protocols. We offer material suitable for research and development purposes, with typical purity levels exceeding 95% (HPLC). Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) documenting identity, purity, and other critical parameters are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.