Description

2-(Methylsulfonyl)-4,6-Diphenylpyrimidine is a high-purity, functionalized pyrimidine derivative characterized by its sulfone and biphenyl substituents, offering a versatile chemical scaffold for advanced synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where its unique structure enables the creation of molecules with targeted biological activity. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its diphenylpyrimidine core.
• Material Science Precursor: Acts as a monomer or functional additive in the research of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme mechanisms and protein-ligand interactions due to its sulfone pharmacophore.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific heterocyclic framework.

Basic Information

Product Name	2-(Methylsulfonyl)-4,6-Diphenylpyrimidine
CAS No.	958727-25-8
Molecular Formula	C17H14N2O2S
Molecular Weight	310.37 g/mol
Synonyms	4,6-Diphenyl-2-(methylsulfonyl)pyrimidine; 2-Methylsulfonyl-4,6-diphenylpyrimidine; 4,6-Diphenyl-2-methylsulfonylpyrimidine; 2-(Methanesulfonyl)-4,6-diphenylpyrimidine; 958727-25-8; 4,6-Diphenyl-2-(methanesulfonyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(Methylsulfonyl)-4,6-Diphenylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.