Description

cis-3-Hydroxymethyl-Cyclohexanecarboxylic Acid Methyl Ester is a high-purity, functionalized cyclohexane derivative that serves as a versatile chiral building block in advanced organic synthesis. Its molecular structure, featuring both a hydroxymethyl and an ester group in a defined cis configuration, makes it a critical intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring defined molecular geometry.
• Ligand and Catalyst Development: Employed in the research and manufacture of chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating polymers with specific functional groups and properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and stereoselective transformations.

Basic Information

Product Name	cis-3-Hydroxymethyl-Cyclohexanecarboxylic Acid Methyl Ester
CAS No.	957996-79-1
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Methyl cis-3-(hydroxymethyl)cyclohexanecarboxylate; (1R,3S)-3-(Hydroxymethyl)cyclohexanecarboxylic acid methyl ester; cis-3-(Hydroxymethyl)cyclohexanecarboxylic acid methyl ester; Methyl 3-(hydroxymethyl)cyclohexanecarboxylate (cis-); Cyclohexanecarboxylic acid, 3-(hydroxymethyl)-, methyl ester, cis-; 957996-79-1
EINECS	Contact for details

Quality Control

Our cis-3-Hydroxymethyl-Cyclohexanecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.