Description

cis-3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester CAS NO 957793-95-2 is a high-value, protected amino acid derivative featuring a constrained cyclobutane ring system. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of novel molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research organizations for the development of new active ingredients, including peptidomimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Peptidomimetic Scaffold: Used to construct conformationally restricted peptide analogs, enhancing metabolic stability and receptor selectivity.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with unique modes of action.
• Chemical Biology Probe: Incorporated into molecular probes to study enzyme function and protein-protein interactions.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric catalysis.
• Academic & Process R&D: Used in research laboratories for method development and scaling novel synthetic routes.

Basic Information

Product Name	cis-3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester
CAS No.	957793-95-2
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	cis-3-Aminocyclobutanecarboxylic acid 1,1-dimethylethyl ester; (1r,3s)-3-Aminocyclobutanecarboxylic acid tert-butyl ester; tert-Butyl cis-3-aminocyclobutanecarboxylate; 3-Aminocyclobutanecarboxylic acid tert-butyl ester, cis-; BOC-3-Amino-cyclobutanecarboxylic acid (cis); cis-3-((tert-Butoxycarbonyl)amino)cyclobutanecarboxylic acid (tautomer); cis-1-N-Boc-3-aminocyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our cis-3-Aminocyclobutanecarboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and enantiomeric excess meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), chiral purity, and related substance profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.