Description

Fmoc-Lys(Boc)-Ser(Psime,Mepro)-Oh CAS NO 957780-54-0 is a protected amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to construct complex peptides with precise stereochemistry and side-chain functionality. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers developing novel therapeutic peptides, peptidomimetics, and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the Fmoc-strategy synthesis of complex peptide sequences, particularly those requiring protected lysine and serine analogs.
• Pharmaceutical Research & Development: Used in the discovery and development of new peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Peptidomimetic Design: Essential for creating modified peptide structures where the Ser(Psime,Mepro) moiety introduces unique conformational or stability properties.
• Bioconjugation & Labeling: Serves as a specialized intermediate for attaching peptides to other molecules, surfaces, or reporter groups via its orthogonal protecting groups.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, medicinal chemistry, and chemical biology focused on protein-protein interactions and signal transduction.

Basic Information

Product Name	Fmoc-Lys(Boc)-Ser(Psime,Mepro)-Oh
CAS No.	957780-54-0
Molecular Formula	C36H51N3O9
Molecular Weight	669.81 g/mol
Synonyms	Fmoc-Lys(Boc)-Ser(ψMe,Mepro)-OH; N-α-Fmoc-N-ε-Boc-L-lysyl-O-(1-methyl-1-propenyl)-L-serine; Fmoc-Lys(Boc)-Ser[ψ(CH3C=CHCH3)]-OH; Fmoc-Lys(Boc)-Ser(ψMe,propenyl)-OH; Fmoc-L-Lys(Boc)-L-Ser(ψMe,Mepro)-OH; (2S)-2-[(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6-{[(2-methylpropan-2-yl)oxy]carbonyl}amino]hexanamido]-3-[(1-methylprop-1-en-1-yl)oxy]propanoic acid; Fmoc-Lys(Boc)-Ser[ψ(Me,C=CHMe)]-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Lys(Boc)-Ser(Psime,Mepro)-Oh is manufactured under strict quality systems to ensure consistency and reliability for critical research and production. Each batch is subjected to rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) detailing purity, chiral integrity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant to maintain stability and prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.