Description

7-Chloro-4-Methyl-2-Oxo-3,4-Dihydro-2 H-Pyrido[1,2-A ]Pyrimidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Academic & Contract Research: Utilized in university and CRO settings for investigating novel heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	7-Chloro-4-Methyl-2-Oxo-3,4-Dihydro-2 H-Pyrido[1,2-A ]Pyrimidine-4-Carboxylic Acid
CAS No.	957503-19-4
Molecular Formula	C10H9ClN2O3
Molecular Weight	240.64 g/mol
Synonyms	7-Chloro-4-methyl-2-oxo-3,4-dihydro-2H-pyrido[1,2-a]pyrimidine-4-carboxylic acid; 4-Carboxy-7-chloro-4-methyl-3,4-dihydro-2H-pyrido[1,2-a]pyrimidin-2-one; 2H-Pyrido[1,2-a]pyrimidine-4-carboxylic acid, 7-chloro-3,4-dihydro-4-methyl-2-oxo-; 957503-19-4; 7-Chloro-4-methyl-2-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Methyl-2-Oxo-3,4-Dihydro-2 H-Pyrido[1,2-A ]Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.