Description

7-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]-Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Research: Used as a scaffold or probe in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and optimization of API manufacturing routes under GMP conditions.
• Academic Research: Employed in medicinal chemistry programs for the discovery of new heterocyclic compounds with potential biological activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of novel chemical entities for clients.

Basic Information

Product Name	7-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]-Pyrimidine-2-Carboxylic Acid
CAS No.	957489-92-8
Molecular Formula	C13H11N5O2
Molecular Weight	269.26 g/mol
Synonyms	Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 7-(1,5-dimethyl-1H-pyrazol-4-yl)-; 7-(1,5-Dimethyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 957489-92-8; 7-(1,5-Dimethylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; AKOS025247315; CS-0446645; FT-0770087; NS00023827; SCHEMBL15545411
EINECS	Contact for details

Quality Control

Our 7-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]-Pyrimidine-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.