Description

3-Methyl-4-Trifluoromethylbenzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role in introducing the trifluoromethyl group, a key pharmacophore known to enhance metabolic stability, lipophilicity, and bioavailability in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, enhancing their dielectric and optical properties.
• Polymer & Material Science: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Organic Synthesis Reagent: Employed in academic and industrial research labs for method development and the construction of diverse fluorinated compound libraries.

Basic Information

Product Name	3-Methyl-4-Trifluoromethylbenzoic Acid Methyl Ester
CAS No.	957205-72-0
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Methyl 3-Methyl-4-(trifluoromethyl)benzoate; 4-(Trifluoromethyl)-3-methylbenzoic Acid Methyl Ester; Benzoic acid, 3-methyl-4-(trifluoromethyl)-, methyl ester; Methyl 4-Trifluoromethyl-m-toluate; 3-Methyl-α,α,α-trifluoro-p-toluic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-Trifluoromethylbenzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.