Description

Thieno[3,2-D]Pyrimidine, 2-(1H-Indazol-4-Yl)-6-[[4-(Methylsulfonyl)-1-Piperazinyl]Methyl]-4-(4-Morpholinyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel kinase inhibitors. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of targeted cancer therapies and other small-molecule drugs. The precise molecular architecture offers a key scaffold for modulating biological activity.

Application

• Pharmaceutical Intermediate: Critical building block in the research and synthesis of novel kinase inhibitors for oncology and inflammatory disease applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays and target validation studies.
• Custom Synthesis: A starting material for the contract manufacturing of active pharmaceutical ingredients (APIs) at developmental and commercial scales.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and biological pathways.

Basic Information

Product Name	Thieno[3,2-D]Pyrimidine, 2-(1H-Indazol-4-Yl)-6-[[4-(Methylsulfonyl)-1-Piperazinyl]Methyl]-4-(4-Morpholinyl)-
CAS No.	957054-50-1
Molecular Formula	C23H29N7O3S2
Molecular Weight	515.66 g/mol
Synonyms	2-(1H-Indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidine; 957054-50-1; Thienopyrimidine-indazole derivative; Kinase inhibitor intermediate; 4-Morpholino-2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.