Description

1-(4,6-Dimethylpyrimidin-2-Yl)Pyrrolidine-2-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a sophisticated intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular architecture is paramount. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides that require specific pyrimidine-based scaffolds for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Acts as a building block for manufacturing specialty chemicals with specific optical or electronic properties.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and the exploration of new chemical reactions involving functionalized heterocycles.

Basic Information

Product Name	1-(4,6-Dimethylpyrimidin-2-Yl)Pyrrolidine-2-Carboxylic Acid
CAS No.	956614-59-8
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	2-Pyrrolidinecarboxylic acid, 1-(4,6-dimethyl-2-pyrimidinyl)-; L-Proline, 1-(4,6-dimethyl-2-pyrimidinyl)-; 1-(4,6-Dimethyl-2-pyrimidinyl)pyrrolidine-2-carboxylic acid; (S)-1-(4,6-Dimethylpyrimidin-2-yl)pyrrolidine-2-carboxylic acid; 956614-59-8; Pyrrolidine-2-carboxylic acid, 1-(4,6-dimethyl-2-pyrimidinyl)-; A potential intermediate for BIBN4096BS (Olcegepant)
EINECS	Contact for details

Quality Control

Every batch of 1-(4,6-Dimethylpyrimidin-2-Yl)Pyrrolidine-2-Carboxylic Acid undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), specific rotation, and impurity profiles is provided with each shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.