Description

4-Piperidinecarboxylicacid,4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)- is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of targeted therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel drug candidates, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for targeted therapies.
• Kinase Inhibitor Development: Serves as a core scaffold for research into novel protein kinase inhibitors due to its pyrrolopyrimidine moiety.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery projects.
• Bioconjugation & Probe Synthesis: Utilized in the creation of biochemical probes and labeled compounds for diagnostic and research applications.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis.

Basic Information

Product Name	4-Piperidinecarboxylicacid,4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-
CAS No.	956460-96-1
Molecular Formula	C17H23N5O4
Molecular Weight	361.40 g/mol
Synonyms	4-((tert-Butoxycarbonyl)amino)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid; 4-(Boc-amino)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)isonipecotic acid; 1-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-4-[(tert-butoxycarbonyl)amino]piperidine-4-carboxylic acid; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxylic acid; 4-(N-Boc-amino)-1-(7-azaindol-4-yl)piperidine-4-carboxylic acid; Boc-protected pyrrolopyrimidine-piperidine carboxylic acid; CAS 956460-96-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support compliance with ICH guidelines for stability and impurity characterization.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.