Description

2-(4-Fluoro-Phenyl)-5-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile pyrazolo[1,5-a]pyrimidine scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Serves as a core scaffold in the development of Active Pharmaceutical Ingredients (APIs), especially for kinase inhibitors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for exploratory drug discovery projects.
• Preclinical Development: Supports the production of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-5-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid
CAS No.	956439-72-8
Molecular Formula	C21H18FN5O2
Molecular Weight	391.40 g/mol
Synonyms	2-(4-Fluorophenyl)-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid; 956439-72-8; Pyrazolo[1,5-a]pyrimidine-7-carboxylic acid, 2-(4-fluorophenyl)-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-; 5-(1,3,5-Trimethyl-1H-pyrazol-4-yl)-2-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-5-(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.