Description

4-Amino-8-Bromo-2-Chloroquinazoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and aminated quinazoline core makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinazoline scaffold.
• Material Science: Serves as a building block for creating specialized organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Amino-8-Bromo-2-Chloroquinazoline
CAS No.	956100-62-2
Molecular Formula	C8H5BrClN3
Molecular Weight	258.50 g/mol
Synonyms	8-Bromo-2-chloro-4-quinazolinamine; 2-Chloro-8-bromo-4-aminoquinazoline; 4-Amino-2-chloro-8-bromoquinazoline; 956100-62-2; Quinazoline, 4-amino-8-bromo-2-chloro-; 8-Bromo-2-chloroquinazolin-4-amine; 4-Amino-8-bromo-2-chloro-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Amino-8-Bromo-2-Chloroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.