Description

4-Amino-1-tert-Butyl-3-(2,3-Dimethylbenzyl)Pyrazolo[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial importance for its role as a critical building block in the synthesis of targeted kinase inhibitors and other bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and inflammatory disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a reference standard and a core scaffold in structure-activity relationship (SAR) studies for drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial structural component in the development of new chemical entities (NCEs) under clinical investigation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of investigational and commercial drugs.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and pharmacological studies.

Basic Information

Product Name	4-Amino-1-tert-Butyl-3-(2,3-Dimethylbenzyl)Pyrazolo[3,4-D]Pyrimidine
CAS No.	956026-24-7
Molecular Formula	C19H25N5
Molecular Weight	323.44 g/mol
Synonyms	4-Amino-1-(tert-butyl)-3-[(2,3-dimethylphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-amino-1-(1,1-dimethylethyl)-3-[(2,3-dimethylphenyl)methyl]-; 4-Amino-1-tert-butyl-3-(2,3-dimethylbenzyl)-1H-pyrazolo[3,4-d]pyrimidine; ATB-DMB-PP; CAS 956026-24-7
EINECS	Contact for details

Quality Control

Our 4-Amino-1-tert-Butyl-3-(2,3-Dimethylbenzyl)Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.