Description

6-Chloromethyl-2-Pyrazin-2-Yl-Pyrimidin-4-Ol is a heterocyclic organic compound featuring a pyrimidine core substituted with both a chloromethyl group and a pyrazinyl moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and building block for medicinal chemistry research. It is primarily utilized in the synthesis of complex molecules, particularly in the development of kinase inhibitors and other targeted therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Fine Chemical Manufacturing: Used in custom synthesis and contract manufacturing of complex, high-value specialty chemicals.
• Academic & Institutional R&D: A critical reagent for universities and research institutes exploring new heterocyclic chemistry and bioactivity.

Basic Information

Product Name	6-Chloromethyl-2-Pyrazin-2-Yl-Pyrimidin-4-Ol
CAS No.	955887-08-8
Molecular Formula	C9H7ClN4O
Molecular Weight	222.63 g/mol
Synonyms	4(3H)-Pyrimidinol, 6-(chloromethyl)-2-(2-pyrazinyl)-; 6-(Chloromethyl)-2-(pyrazin-2-yl)pyrimidin-4-ol; 2-(6-Chloromethyl-4-hydroxypyrimidin-2-yl)pyrazine; 6-(Chloromethyl)-2-pyrazin-2-yl-1H-pyrimidin-4-one; 6-(Chloromethyl)-2-(2-pyrazinyl)-4-pyrimidinol; 955887-08-8; Pyrazinyl-pyrimidine derivative
EINECS	Contact for details

Quality Control

Our 6-Chloromethyl-2-Pyrazin-2-Yl-Pyrimidin-4-Ol is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.