Description

L-Isothreonine Hcl is a high-purity, non-proteinogenic amino acid derivative essential for advanced biochemical research and pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate, enabling the development of novel peptides, active pharmaceutical ingredients (APIs), and complex organic molecules. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical producers focused on drug discovery, proteomics, and the synthesis of specialized bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based drugs, antibiotics, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a non-standard amino acid in proteomics research, enzyme studies, and metabolic pathway investigations.
• Peptide Synthesis: Serves as a specialized building block in solid-phase and solution-phase peptide synthesis for creating custom peptides with unique properties.
• Agrochemical Development: Employed in the research and development of advanced, chiral agrochemicals and plant growth regulators.
• Diagnostic Reagents: A component in the formulation of specialized diagnostic kits and reagents for clinical and research laboratories.
• Nutritional Science Research: Investigated for its role and effects in specialized nutritional and metabolic studies.

Basic Information

Product Name	L-Isothreonine Hcl
CAS No.	955375-67-4
Molecular Formula	C4H9NO3 • HCl
Molecular Weight	155.58 g/mol (Free base: 119.12 g/mol)
Synonyms	(2S,3S)-2-Amino-3-hydroxybutanoic acid hydrochloride; L-threo-Isothreonine hydrochloride; (2S,3S)-3-Hydroxy-L-threonine hydrochloride; L-β-Hydroxynorvaline hydrochloride; L-Isothreonine hydrochloride; L-iso-Thr-OH • HCl; L-threo-2-Amino-3-hydroxybutyric acid hydrochloride
EINECS	Contact for details

Quality Control

Our L-Isothreonine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-threo isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.