Description

2,4-Bis-(Trifluoromethyl)-Aniline is a high-value fluorinated aromatic amine building block, distinguished by its two electron-withdrawing trifluoromethyl groups. This unique structure imparts exceptional chemical stability and lipophilicity, making it a critical intermediate for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to manufacture advanced herbicides, fungicides, and insecticides, where the CF3 groups improve metabolic stability and bioavailability.
• Liquid Crystal Materials: Serves as a core component in the production of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Building block for electron-transport materials, semiconductors, and other functional materials in OLEDs and organic photovoltaics.
• Dye and Pigment Industry: Intermediate for creating specialized, light-fast fluorinated dyes and pigments.
• Polymer Modification: Used to introduce fluorine into polymer chains, enhancing chemical resistance, thermal stability, and surface properties of advanced plastics and coatings.

Basic Information

Product Name	2,4-Bis-(Trifluoromethyl)-Aniline
CAS No.	167-71-5
Molecular Formula	C8H5F6N
Molecular Weight	229.13 g/mol
Synonyms	2,4-Bis(trifluoromethyl)aniline; 2,4-Bis(trifluoromethyl)benzenamine; α,α,α,α',α',α'-Hexafluoro-2,4-xylidine; 2,4-Di(trifluoromethyl)aniline; 2-Amino-1,3-bis(trifluoromethyl)benzene; 2,4-Bis(trifluoromethyl)phenylamine; Benzenamine, 2,4-bis(trifluoromethyl)-
EINECS	205-710-5

Quality Control

Every batch of 2,4-Bis-(Trifluoromethyl)-Aniline is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is compatible with most organic solvents but is moisture-sensitive; keep container tightly sealed under an inert atmosphere for optimal shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.