Description

5-Fluoro-Dl-Tryptophan is a fluorinated derivative of the essential amino acid tryptophan, distinguished by the substitution of a fluorine atom at the 5-position of the indole ring. This structural modification is critical for its role as a biochemical building block and research tool, offering unique electronic and steric properties that influence protein structure and function. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for applications ranging from drug discovery to metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel fluorinated drug candidates and bioactive peptides.
• Biochemical Research: Used as a non-natural amino acid in protein engineering and structure-activity relationship (SAR) studies to investigate enzyme mechanisms and protein folding.
• Metabolic Pathway Analysis: Employed as a tracer or analog in metabolic studies to understand tryptophan utilization and fluorine's impact on biological systems.
• Agrochemical Development: Acts as a building block for creating advanced fluorinated pesticides and plant growth regulators.
• Peptide Synthesis: Incorporated into custom peptides to enhance stability, modulate bioavailability, or create specific receptor ligands.
• Academic & Industrial R&D: Fundamental material for exploring fluorine chemistry in life sciences and material science applications.

Basic Information

Product Name	5-Fluoro-Dl-Tryptophan
CAS No.	154-08-5
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	5-Fluoro-DL-tryptophan; DL-5-Fluorotryptophan; (±)-5-Fluorotryptophan; 5-Fluoro-1H-indole-3-alanine; 2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid; 5-F-Trp; 5-Fluoro-DL-α-tryptophan; 5-Fluorotryptophan, DL-
EINECS	205-819-5

Quality Control

Our 5-Fluoro-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets rigorous research and pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.