Description

2,4,5-Trifluoro-6-Bromoaniline is a high-value, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of bromine and fluorine substituents on the aniline core makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology treatments.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing charge-transport materials, host materials, and emissive layer components in display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as chemical resistance, thermal stability, or altered refractive index.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form complex biaryl and aryl amine structures.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2,4,5-Trifluoro-6-Bromoaniline
CAS No.	1481-21-6
Molecular Formula	C6H2BrF3N
Molecular Weight	225.99 g/mol
Synonyms	6-Bromo-2,4,5-trifluoroaniline; 2,4,5-Trifluoro-6-bromobenzenamine; 2-Bromo-4,5,6-trifluoroaniline; Benzenamine, 6-bromo-2,4,5-trifluoro-; 1481-21-6; 6-Bromo-2,4,5-trifluorophenylamine; 2,4,5-Trifluoro-6-bromo-phenylamine
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-6-Bromoaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.