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2-Aminoheptafluoronaphtalene CAS NO 1146-66-3
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CAS No.:1146-66-3
Grade:Pharmacy Grade
Content:99.0%
Brand:Customizable
Packaging:Customizable
Description
2-Aminoheptafluoronaphtalene is a high-purity, fluorinated aromatic amine building block of significant importance in advanced chemical synthesis. Its unique structure, featuring a naphthalene core with extensive fluorine substitution and a single amino group, makes it a critical intermediate for creating specialized materials with enhanced stability and specific electronic properties. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is required to modulate biological activity, chemical inertness, or material characteristics.
Application
- Pharmaceutical Intermediate: Serves as a key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics, where fluorine atoms can improve metabolic stability and membrane permeability.
- Agrochemical Synthesis: Used in the research and manufacture of next-generation herbicides and pesticides, leveraging the lipophilicity and stability imparted by the heptafluoronaphtalene moiety.
- Advanced Material Precursor: Acts as a monomer or functionalizing agent in the synthesis of fluorinated polymers, liquid crystals, and organic semiconductors for electronics and optics applications.
- Chemical Research & Development: Employed as a versatile scaffold in organic chemistry for studying nucleophilic aromatic substitution and developing novel fluorination methodologies.
- Dye and Pigment Intermediate: Utilized in the creation of specialized fluorinated dyes and pigments that offer superior lightfastness and chemical resistance.
Basic Information
| Product Name | 2-Aminoheptafluoronaphtalene |
| CAS No. | 1146-66-3 |
| Molecular Formula | C₁₀H₂F₇N |
| Molecular Weight | 269.12 g/mol |
| Synonyms | 2-Aminoheptafluoronaphthalene; 1,2,3,4,5,6,7-Heptafluoro-8-aminonaphthalene; Perfluoro-2-aminonaphthalene; 8-Aminoperfluoronaphthalene; 2-Amino-1,3,4,5,6,7,8-heptafluoronaphthalene; Heptafluoro-2-naphthylamine; 1146-66-3 (CAS Registry) |
| EINECS | Contact for details |
Quality Control
Our 2-Aminoheptafluoronaphtalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee traceability and consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere to minimize potential degradation and handled in accordance with good laboratory practices for amines.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 10 ppm |
| Residue on Ignition | < 0.1% |
| Water Content (KF) | < 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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