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2-Aminoheptafluoronaphtalene CAS NO 1146-66-3


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CAS No.:1146-66-3

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

2-Aminoheptafluoronaphtalene is a high-purity, fluorinated aromatic amine building block of significant importance in advanced chemical synthesis. Its unique structure, featuring a naphthalene core with extensive fluorine substitution and a single amino group, makes it a critical intermediate for creating specialized materials with enhanced stability and specific electronic properties. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is required to modulate biological activity, chemical inertness, or material characteristics.

Application

  • Pharmaceutical Intermediate: Serves as a key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics, where fluorine atoms can improve metabolic stability and membrane permeability.
  • Agrochemical Synthesis: Used in the research and manufacture of next-generation herbicides and pesticides, leveraging the lipophilicity and stability imparted by the heptafluoronaphtalene moiety.
  • Advanced Material Precursor: Acts as a monomer or functionalizing agent in the synthesis of fluorinated polymers, liquid crystals, and organic semiconductors for electronics and optics applications.
  • Chemical Research & Development: Employed as a versatile scaffold in organic chemistry for studying nucleophilic aromatic substitution and developing novel fluorination methodologies.
  • Dye and Pigment Intermediate: Utilized in the creation of specialized fluorinated dyes and pigments that offer superior lightfastness and chemical resistance.

Basic Information

Product Name 2-Aminoheptafluoronaphtalene
CAS No. 1146-66-3
Molecular Formula C₁₀H₂F₇N
Molecular Weight 269.12 g/mol
Synonyms 2-Aminoheptafluoronaphthalene; 1,2,3,4,5,6,7-Heptafluoro-8-aminonaphthalene; Perfluoro-2-aminonaphthalene; 8-Aminoperfluoronaphthalene; 2-Amino-1,3,4,5,6,7,8-heptafluoronaphthalene; Heptafluoro-2-naphthylamine; 1146-66-3 (CAS Registry)
EINECS Contact for details

Quality Control

Our 2-Aminoheptafluoronaphtalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere to minimize potential degradation and handled in accordance with good laboratory practices for amines.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Heavy Metals < 10 ppm
Residue on Ignition < 0.1%
Water Content (KF) < 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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