Description

2-Bromo-5-Fluoroaniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine atoms on the aromatic ring, enabling selective functionalization and the introduction of unique physicochemical properties into target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine substituents enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex organic dyes and pigments, contributing to color fastness and specific spectral properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical reactions, catalytic processes, and structure-activity relationships.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings, facilitating carbon-carbon and carbon-heteroatom bond formation.

Basic Information

Product Name	2-Bromo-5-Fluoroaniline
CAS No.	1003-99-2
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	5-Fluoro-2-bromoaniline; 2-Bromo-5-fluoro-benzenamine; 1-Amino-2-bromo-5-fluorobenzene; Benzenamine, 2-bromo-5-fluoro-; 2-Bromo-5-fluoro-phenylamine; 2-Bromo-5-fluoroaniline (primary name); 5-Fluoro-o-bromoaniline; (2-Bromo-5-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable, and our quality commitment supports compliance with global regulatory frameworks such as REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.