Description

2-Amino-5-Nitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate characterized by its amino and nitro substituents on a trifluoromethylated benzene ring. This unique structure makes it a critical building block for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for manufacturers and R&D teams developing active ingredients, dyes, and advanced materials who require a reliable supply of high-purity specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a core intermediate for creating high-performance, light-fast azo dyes and organic pigments.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and electronic materials due to its electron-withdrawing properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	2-Amino-5-Nitrobenzotrifluoride
CAS No.	121-01-7
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	2-Amino-5-nitro-α,α,α-trifluorotoluene; 5-Nitro-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-5-nitroaniline; 2-Trifluoromethyl-5-nitroaniline; 5-Nitro-α,α,α-trifluoro-o-toluidine; Benzenamine, 2-(trifluoromethyl)-5-nitro-; 2-Amino-α,α,α-trifluoro-5-nitrotoluene
EINECS	204-441-6

Quality Control

Our 2-Amino-5-Nitrobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.