Description

2-Bromo-4-Fluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a valuable intermediate for introducing specific functional groups and modifying electronic properties in target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the bromo-fluoroaniline moiety contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for creating specialized azo dyes and pigments with enhanced color fastness and stability.
• Polymer Modification: Used to synthesize functional monomers and additives that impart specific properties to high-performance polymers.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	2-Bromo-4-Fluoroaniline
CAS No.	1003-98-1
Molecular Formula	C6H5BrFN
Molecular Weight	190.01 g/mol
Synonyms	2-Bromo-4-fluoroaniline; 4-Fluoro-2-bromoaniline; 2-Bromo-4-fluoro-benzenamine; 1-Amino-2-bromo-4-fluorobenzene; Benzenamine, 2-bromo-4-fluoro-; Aniline, 2-bromo-4-fluoro-; 2-Br-4-F-aniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.