Description

2-(2-Amino-5-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile is a specialized heterocyclic organic compound featuring a trifluoromethyl group and an amino-substituted phenyl ring, making it a valuable fluorinated building block. This high-purity intermediate is critical for research and development in advanced pharmaceutical and agrochemical synthesis, where its unique structure enables the introduction of desirable physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Acts as a precursor for synthesizing specialized fluorinated organic compounds used in electronic materials and functional polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-(2-Amino-5-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile
CAS No.	917607-76-2
Molecular Formula	C16H10F3N3
Molecular Weight	301.27 g/mol
Synonyms	2-(2-Amino-5-(trifluoromethyl)phenyl)isoindole-1-carbonitrile; 2-(2-Amino-α,α,α-trifluoro-p-tolyl)-2H-isoindole-1-carbonitrile; 2H-Isoindole-1-carbonitrile, 2-[2-amino-5-(trifluoromethyl)phenyl]-; 917607-76-2; 2-(2-Amino-5-trifluoromethylphenyl)-2H-isoindole-1-carbonitrile; 2-(2-Amino-5-(trifluoromethyl)phenyl)-1-cyanoisoindole
EINECS	Contact for details

Quality Control

Our 2-(2-Amino-5-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.