Description

2-Allyl-1-(6-(2-Hydroxypropan-2-Yl)Pyridin-2-Yl)-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized by the pharmaceutical and biotechnology industries for research and development, as well as in the production of active pharmaceutical ingredients (APIs) for various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors.
• Biochemical Research: Used as a reference standard or a core scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• API Synthesis: Serves as a critical building block in the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Oncology Drug Development: Employed in the research and production of targeted cancer therapies due to the biological relevance of the pyrazolopyrimidine core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthesis and pharmacological testing of new chemical entities.

Basic Information

Product Name	2-Allyl-1-(6-(2-Hydroxypropan-2-Yl)Pyridin-2-Yl)-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One
CAS No.	955369-56-9
Molecular Formula	C18H19N5O2S
Molecular Weight	369.44 g/mol
Synonyms	2-Allyl-1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-(methylthio)-2,3-dihydro-1H-pyrazolo[3,4-d]pyrimidin-3-one; 6-(Methylthio)-2-allyl-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one; 1H-Pyrazolo[3,4-d]pyrimidin-3(2H)-one, 2-allyl-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-(methylthio)-; Pyrazolopyrimidine derivative CAS 955369-56-9
EINECS	Contact for details

Quality Control

Our 2-Allyl-1-(6-(2-Hydroxypropan-2-Yl)Pyridin-2-Yl)-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidin-3(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring a reliable supply for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.